SCOPe 2.08: Domain d1cmwa8: 1cmw A:423-832

Lineage for d1cmwa8 (1cmw A:423-832)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)
   in the multi-domain class (e), this applies to domains with different numbers of (sub)domains than the most common domain
   

6. Protein DNA polymerase I (Klenow fragment) [56674] (3 species)

7. Species Thermus aquaticus [TaxId:271] [56676] (29 PDB entries)

8. Domain d1cmwa8: 1cmw A:423-832 [302291]
   Other proteins in same PDB: d1cmwa5, d1cmwa6, d1cmwa7
   automated match to d1bgxt4

Details for d1cmwa8

PDB Entry: 1cmw, 2.6 Å

PDB Description: crystal structure of taq dna-polymerase shows a new orientation for the structure-specific nuclease domain

PDB Compounds: (A:) protein (DNA polymerase I)

SCOPe Domain Sequences for d1cmwa8:

Sequence, based on SEQRES records:

>d1cmwa8 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus [TaxId: 271]}
eerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlaghpf
nlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklk
styidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaee
gwllvaldysqielrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrraa
ktinfgvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyvet
lfgrrryvpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarmllq
vhdelvleapkeraeavarlakevmegvyplavplevevgigedwlsake

Sequence, based on observed residues (ATOM records):

>d1cmwa8 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus [TaxId: 271]}
eerllwlyreverplsavlahmeatgvrldvaylralslevaleaevfrlaghpfnlnsr
dqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklkstyid
plpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaeegwllv
aldysqielrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrraaktinf
gvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyvetlfgrr
ryvpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarmllqvhdel
vleapkeraeavarlakevmegvyplavplevevgigedwlsake

Timeline for d1cmwa8:

• d1cmwa8 first appeared in SCOPe 2.06
  
• d1cmwa8 appears in SCOPe 2.07