SCOPe 2.08: Domain d1cmwa7: 1cmw A:290-422

Lineage for d1cmwa7 (1cmw A:290-422)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (18 families)
   consists of one domain of this fold

5. Family c.55.3.5: DnaQ-like 3'-5' exonuclease [53118] (17 proteins)
   contains Pfam PF00929

6. Protein Exonuclease domain of prokaryotic DNA polymerase [53119] (3 species)
   part of Klenow fragment, KF

7. Species Thermus aquaticus [TaxId:271] [53121] (29 PDB entries)

8. Domain d1cmwa7: 1cmw A:290-422 [302290]
   Other proteins in same PDB: d1cmwa5, d1cmwa6, d1cmwa8
   automated match to d1bgxt3

Details for d1cmwa7

PDB Entry: 1cmw, 2.6 Å

PDB Description: crystal structure of taq dna-polymerase shows a new orientation for the structure-specific nuclease domain

PDB Compounds: (A:) protein (DNA polymerase I)

SCOPe Domain Sequences for d1cmwa7:

Sequence, based on SEQRES records:

>d1cmwa7 c.55.3.5 (A:290-422) Exonuclease domain of prokaryotic DNA polymerase {Thermus aquaticus [TaxId: 271]}
spkaleeapwpppegafvgfvlsrkepmwadllalaaarggrvhrapepykalrdlkear
gllakdlsvlalreglglppgddpmllaylldpsnttpegvarryggewteeageraals
erlfanlwgrleg

Sequence, based on observed residues (ATOM records):

>d1cmwa7 c.55.3.5 (A:290-422) Exonuclease domain of prokaryotic DNA polymerase {Thermus aquaticus [TaxId: 271]}
spaleeapwpppegafvgfvlsrkepmwadllalaaarggrvhrapepykalrdlkearg
llakdlsvlalreglglppgddpmllaylldpsnttpegvarryggewteeageraalse
rlfanlwgrleg

Timeline for d1cmwa7:

• d1cmwa7 first appeared in SCOPe 2.06
  
• d1cmwa7 appears in SCOPe 2.07