SCOPe 2.06: Domain d1aupa1: 1aup A:205-449

Lineage for d1aupa1 (1aup A:205-449)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (12 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Glutamate dehydrogenase [51884] (8 species)

7. Species Clostridium symbiosum [TaxId:1512] [51885] (4 PDB entries)

8. Domain d1aupa1: 1aup A:205-449 [30222]
   Other proteins in same PDB: d1aupa2

Details for d1aupa1

PDB Entry: 1aup, 2.5 Å

PDB Description: glutamate dehydrogenase

PDB Compounds: (A:) nad-specific glutamate dehydrogenase

SCOPe Domain Sequences for d1aupa1:

Sequence, based on SEQRES records:

>d1aupa1 c.2.1.7 (A:205-449) Glutamate dehydrogenase {Clostridium symbiosum [TaxId: 1512]}
rpeatgygsvyyveavmkhendtlvgktvalagfgnvawgaakklaelgakavtlsgpdg
yiydpegitteekinymlemrasgrnkvqdyadkfgvqffpgekpwgqkvdiimpcatqn
dvdleqakkivannvkyyievanmpttnealrflmqqpnmvvapskavnaggvlvvgfem
sqnserlswtaeevdsklhqvmtdihdgsaaaaeryglgynlvaganivgfqkiadamma
qgiaw

Sequence, based on observed residues (ATOM records):

>d1aupa1 c.2.1.7 (A:205-449) Glutamate dehydrogenase {Clostridium symbiosum [TaxId: 1512]}
rpeatgygsvyyveavmkhendtlvgktvalagfgnvawgaakklaelgakavtlsgpdg
yiydpegitteekinymlemrasgrnkvqdyadkfgvqffpgekpwgqkvdiimpcatqn
dvdleqakkivannvkyyievanmpttnealrflmqqpnmvvapskavnaggvlvvgfet
aeevdsklhqvmtdihdgsaaaaeryglgynlvaganivgfqkiadammaqgiaw

Timeline for d1aupa1:

• d1aupa1 first appeared (with stable ids) in SCOP 1.55, called d1aup_1
  
• d1aupa1 appears in SCOPe 2.05
  
• d1aupa1 appears in SCOPe 2.07
  
• d1aupa1 appears in the current release, SCOPe 2.08