SCOP 1.69: Domain d1aup_1: 1aup 205-449

Lineage for d1aup_1 (1aup 205-449)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (11 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Glutamate dehydrogenase [51884] (7 species)

7. Species Clostridium symbiosum [TaxId:1512] [51885] (4 PDB entries)

8. Domain d1aup_1: 1aup 205-449 [30222]
   Other proteins in same PDB: d1aup_2

Details for d1aup_1

PDB Entry: 1aup, 2.5 Å

PDB Description: glutamate dehydrogenase

SCOP Domain Sequences for d1aup_1:

Sequence, based on SEQRES records:

>d1aup_1 c.2.1.7 (205-449) Glutamate dehydrogenase {Clostridium symbiosum}
rpeatgygsvyyveavmkhendtlvgktvalagfgnvawgaakklaelgakavtlsgpdg
yiydpegitteekinymlemrasgrnkvqdyadkfgvqffpgekpwgqkvdiimpcatqn
dvdleqakkivannvkyyievanmpttnealrflmqqpnmvvapskavnaggvlvvgfem
sqnserlswtaeevdsklhqvmtdihdgsaaaaeryglgynlvaganivgfqkiadamma
qgiaw

Sequence, based on observed residues (ATOM records):

>d1aup_1 c.2.1.7 (205-449) Glutamate dehydrogenase {Clostridium symbiosum}
rpeatgygsvyyveavmkhendtlvgktvalagfgnvawgaakklaelgakavtlsgpdg
yiydpegitteekinymlemrasgrnkvqdyadkfgvqffpgekpwgqkvdiimpcatqn
dvdleqakkivannvkyyievanmpttnealrflmqqpnmvvapskavnaggvlvvgfet
aeevdsklhqvmtdihdgsaaaaeryglgynlvaganivgfqkiadammaqgiaw

Timeline for d1aup_1:

• d1aup_1 first appeared (with stable ids) in SCOP 1.55
  
• d1aup_1 appears in SCOP 1.67
  
• d1aup_1 appears in SCOP 1.71
  
• d1aup_1 appears in the current release, SCOPe 2.08, called d1aupa1