SCOP 1.75: Domain d1qkid1: 1qki D:10-199,D:435-449

Lineage for d1qkid1 (1qki D:10-199,D:435-449)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

6. Protein Glucose 6-phosphate dehydrogenase, N-terminal domain [51827] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [51829] (1 PDB entry)

8. Domain d1qkid1: 1qki D:10-199,D:435-449 [30083]
   Other proteins in same PDB: d1qkia2, d1qkib2, d1qkic2, d1qkid2, d1qkie2, d1qkif2, d1qkig2, d1qkih2

Details for d1qkid1

PDB Entry: 1qki, 3 Å

PDB Description: x-ray structure of human glucose 6-phosphate dehydrogenase (variant canton r459l) complexed with structural nadp+

PDB Compounds: (D:) glucose-6-phosphate 1-dehydrogenase

SCOP Domain Sequences for d1qkid1:

Sequence, based on SEQRES records:

>d1qkid1 c.2.1.3 (D:10-199,D:435-449) Glucose 6-phosphate dehydrogenase, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
thvcgilreelfqgdafhqsdthifiimgasgdlakkkiyptiwwlfrdgllpentfivg
yarsrltvadirkqsepffkatpeeklkledffarnsyvagqyddaasyqrlnshmnalh
lgsqanrlfylalpptvyeavtknihescmsqigwnriivekpfgrdlqssdrlsnhiss
lfredqiyriXdayerlildvfcgsq

Sequence, based on observed residues (ATOM records):

>d1qkid1 c.2.1.3 (D:10-199,D:435-449) Glucose 6-phosphate dehydrogenase, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
thvcgiqsdthifiimgasgdlakkkiyptiwwlfrdgllpentfivgyarsrltvadir
kqsepffkatpeeklkledffarnsyvagqyddaasyqrlnshmnalhlgsqanrlfyla
lpptvyeavtknihescmsqigwnriivekpfgrdlqssdrlsnhisslfredqiyriXd
ayerlildvfcgsq

Timeline for d1qkid1:

• d1qkid1 first appeared (with stable ids) in SCOP 1.55
  
• d1qkid1 appears in SCOP 1.73
  
• d1qkid1 appears in SCOPe 2.01
  
• d1qkid1 appears in the current release, SCOPe 2.08