SCOP 1.75: Domain d2ae2a_: 2ae2 A:

Lineage for d2ae2a_ (2ae2 A:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Tropinone reductase [51795] (3 species)

7. Species Jimsonweed (Datura stramonium), II [TaxId:4076] [51797] (4 PDB entries)

8. Domain d2ae2a_: 2ae2 A: [29945]

Details for d2ae2a_

PDB Entry: 2ae2, 1.9 Å

PDB Description: tropinone reductase-ii complexed with nadp+ and pseudotropine

PDB Compounds: (A:) protein (tropinone reductase-II)

SCOP Domain Sequences for d2ae2a_:

Sequence; same for both SEQRES and ATOM records:

>d2ae2a_ c.2.1.2 (A:) Tropinone reductase {Jimsonweed (Datura stramonium), II [TaxId: 4076]}
agrwnlegctalvtggsrgigygiveelaslgasvytcsrnqkelndcltqwrskgfkve
asvcdlssrserqelmntvanhfhgklnilvnnagiviykeakdytvedyslimsinfea
ayhlsvlahpflkasergnvvfissvsgalavpyeavygatkgamdqltrclafewakdn
irvngvgpgviatslvemtiqdpeqkenlnklidrcalrrmgepkelaamvaflcfpaas
yvtgqiiyvdgglmancgf

Timeline for d2ae2a_:

• d2ae2a_ first appeared (with stable ids) in SCOP 1.55
  
• d2ae2a_ appears in SCOP 1.73
  
• d2ae2a_ appears in SCOPe 2.01
  
• d2ae2a_ appears in the current release, SCOPe 2.08