SCOPe 2.01: Domain d1d8ab_: 1d8a B:

Lineage for d1d8ab_ (1d8a B:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Enoyl-ACP reductase [51791] (10 species)

7. Species Escherichia coli [TaxId:562] [51794] (13 PDB entries)

8. Domain d1d8ab_: 1d8a B: [29932]
   complexed with nad, tcl

Details for d1d8ab_

PDB Entry: 1d8a, 2.2 Å

PDB Description: e. coli enoyl reductase/nad+/triclosan complex

PDB Compounds: (B:) Enoyl-[acyl-carrier-protein] reductase

SCOPe Domain Sequences for d1d8ab_:

Sequence; same for both SEQRES and ATOM records:

>d1d8ab_ c.2.1.2 (B:) Enoyl-ACP reductase {Escherichia coli [TaxId: 562]}
gflsgkrilvtgvasklsiaygiaqamhregaelaftyqndklkgrveefaaqlgsdivl
qcdvaedasidtmfaelgkvwpkfdgfvhsigfapgdqldgdyvnavtregfkiahdiss
ysfvamakacrsmlnpgsalltlsylgaeraipnynvmglakasleanvrymanamgpeg
vrvnaisagpirtlaasgikdfrkmlahceavtpirrtvtiedvgnsaaflcsdlsagis
gevvhvdggfsiaamne

Timeline for d1d8ab_:

• d1d8ab_ first appeared (with stable ids) in SCOP 1.55
  
• d1d8ab_ appears in SCOP 1.75
  
• d1d8ab_ appears in SCOPe 2.02
  
• d1d8ab_ appears in the current release, SCOPe 2.08