Lineage for d1fk8a_ (1fk8 A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2090752Protein 3-alpha-hydroxysteroid dehydrogenase [51778] (1 species)
  7. 2090753Species Comamonas testosteroni [TaxId:285] [51779] (2 PDB entries)
  8. 2090756Domain d1fk8a_: 1fk8 A: [29872]
    complexed with nad

Details for d1fk8a_

PDB Entry: 1fk8 (more details), 1.95 Å

PDB Description: the crystal structure of the binary complex with nad of 3-alpha- hydroxysteroid dehydrogenase from comamonas testosteroni, a member of the short chain dehydrogenase/reductase family
PDB Compounds: (A:) 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase

SCOPe Domain Sequences for d1fk8a_:

Sequence, based on SEQRES records: (download)

>d1fk8a_ c.2.1.2 (A:) 3-alpha-hydroxysteroid dehydrogenase {Comamonas testosteroni [TaxId: 285]}
msiivisgcatgigaatrkvleaaghqivgidirdaeviadlstaegrkqaiadvlakcs
kgmdglvlcaglgpqtkvlgnvvsvnyfgatelmdaflpalkkghqpaavvissvasahl
afdknplalaleageeakaraivehageqggnlayagsknaltvavrkraaawgeagvrl
ntiapgatetpllqaglqdprygesiakfvppmgrraepsemasviaflmspaasyvhga
qividggidavmrptqf

Sequence, based on observed residues (ATOM records): (download)

>d1fk8a_ c.2.1.2 (A:) 3-alpha-hydroxysteroid dehydrogenase {Comamonas testosteroni [TaxId: 285]}
msiivisgcatgigaatrkvleaaghqivgidirdaeviadlstaegrkqaiadvlakcs
kgmdglvlcaglgpqtkvlgnvvsvnyfgatelmdaflpalkkghqpaavvissvasahl
afdknplalaleageeakaraivehageqggnlayagsknaltvavrkraaawgeagvrl
ntiapgatetpfvppmgrraepsemasviaflmspaasyvhgaqividggidavmrptqf

SCOPe Domain Coordinates for d1fk8a_:

Click to download the PDB-style file with coordinates for d1fk8a_.
(The format of our PDB-style files is described here.)

Timeline for d1fk8a_: