Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) |
Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 has additional subdomain(s) that are not in the common domain |
Protein 3-alpha,20-beta-hydroxysteroid dehydrogenase [51776] (1 species) |
Species Streptomyces hydrogenans [TaxId:1905] [51777] (2 PDB entries) |
Domain d1hdcd_: 1hdc D: [29865] complexed with cbo |
PDB Entry: 1hdc (more details), 2.2 Å
SCOPe Domain Sequences for d1hdcd_:
Sequence, based on SEQRES records: (download)
>d1hdcd_ c.2.1.2 (D:) 3-alpha,20-beta-hydroxysteroid dehydrogenase {Streptomyces hydrogenans [TaxId: 1905]} ndlsgktviitggarglgaeaarqavaagarvvladvldeegaatarelgdaaryqhldv tieedwqrvvayareefgsvdglvnnagistgmfletesverfrkvveinltgvfigmkt vipamkdagggsivnissaaglmglaltssygaskwgvrglsklaavelgtdrirvnsvh pgmtytpmtaetgirqgegnypntpmgrvgnepgeiagavvkllsdtssyvtgaelavdg gwttgptvkyvmgq
>d1hdcd_ c.2.1.2 (D:) 3-alpha,20-beta-hydroxysteroid dehydrogenase {Streptomyces hydrogenans [TaxId: 1905]} ndlsgktviitggarglgaeaarqavaagarvvladvldeegaatarelgdaaryqhldv tieedwqrvvayareefgsvdglvnnagistgmfletesverfrkvveinltgvfigmkt vipamkdagggsivnissaaglmglaltssygaskwgvrglsklaavelgtdrirvnsvh pgmtytpmtaetgirqgegnypntpmgrvgepgeiagavvkllsdtssyvtgaelavdgg wttgptvkyvmgq
Timeline for d1hdcd_: