SCOPe 2.08: Domain d4ijwd2: 4ijw D:10-10

Lineage for d4ijwd2 (4ijw D:10-10)

1. Root: SCOPe 2.08

2. Class l: Artifacts [310555] (1 fold)

3. Fold l.1: Tags [310573] (1 superfamily)

4. Superfamily l.1.1: Tags [310607] (1 family)

5. Family l.1.1.1: Tags [310682] (2 proteins)

6. Protein N-terminal Tags [310894] (1 species)

7. Species Synthetic [311501] (15360 PDB entries)

8. Domain d4ijwd2: 4ijw D:10-10 [298419]
   Other proteins in same PDB: d4ijwa_, d4ijwb1, d4ijwd1, d4ijwe_
   complexed with 1eq, nap; mutant

Details for d4ijwd2

PDB Entry: 4ijw, 2.35 Å

PDB Description: Crystal structure of 11b-HSD1 double mutant (L262R, F278E) in complex with 3-[1-(4-chlorophenyl)cyclopropyl]-8-cyclopropyl[1,2,4]triazolo[4,3-a]pyridine

PDB Compounds: (D:) Corticosteroid 11-beta-dehydrogenase isozyme 1

SCOPe Domain Sequences for d4ijwd2:

Sequence; same for both SEQRES and ATOM records:

>d4ijwd2 l.1.1.1 (D:10-10) N-terminal Tags {Synthetic}
m

Timeline for d4ijwd2:

• d4ijwd2 first appeared in SCOPe 2.06
  
• d4ijwd2 appears in SCOPe 2.07