SCOP 1.69: Domain d1bhs__: 1bhs -

Lineage for d1bhs__ (1bhs -)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (45 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Human estrogenic 17beta-hydroxysteroid dehydrogenase [51772] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [51773] (16 PDB entries)

8. Domain d1bhs__: 1bhs - [29840]

Details for d1bhs__

PDB Entry: 1bhs, 2.2 Å

PDB Description: human estrogenic 17beta-hydroxysteroid dehydrogenase

SCOP Domain Sequences for d1bhs__:

Sequence; same for both SEQRES and ATOM records:

>d1bhs__ c.2.1.2 (-) Human estrogenic 17beta-hydroxysteroid dehydrogenase {Human (Homo sapiens)}
artvvlitgcssgiglhlavrlasdpsqsfkvyatlrdlktqgrlweaaralacppgsle
tlqldvrdsksvaaarervtegrvdvlvcnaglgllgplealgedavasvldvnvvgtvr
mlqaflpdmkrrgsgrvlvtgsvgglmglpfndvycaskfaleglceslavlllpfgvhl
sliecgpvhtafmekvlgspeevldrtdihtfhrfyqylahskqvfreaaqnpeevaevf
ltalrapkptlryftterflpllrmrlddpsgsnyvtamhrevf

Timeline for d1bhs__:

• d1bhs__ first appeared (with stable ids) in SCOP 1.55
  
• d1bhs__ appears in SCOP 1.67
  
• d1bhs__ appears in SCOP 1.71
  
• d1bhs__ appears in the current release, SCOPe 2.08, called d1bhsa_