SCOPe 2.06: Domain d1dird_: 1dir D:

Lineage for d1dird_ (1dir D:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Dihydropteridin reductase (pteridine reductase) [51769] (7 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [51770] (2 PDB entries)

8. Domain d1dird_: 1dir D: [29836]
   complexed with nad

Details for d1dird_

PDB Entry: 1dir, 2.6 Å

PDB Description: crystal structure of a monoclinic form of dihydropteridine reductase from rat liver

PDB Compounds: (D:) Dihydropteridine reductase

SCOPe Domain Sequences for d1dird_:

Sequence; same for both SEQRES and ATOM records:

>d1dird_ c.2.1.2 (D:) Dihydropteridin reductase (pteridine reductase) {Norway rat (Rattus norvegicus) [TaxId: 10116]}
earrvlvyggrgalgsrcvqafrarnwwvasidvveneeasasvivkmtdsfteqadqvt
aevgkllgdqkvdailcvaggwaggnakskslfkncdlmwkqsiwtstisshlatkhlke
gglltlagakaaldgtpgmigygmakgavhqlcqslagknsgmpsgaaaiavlpvtldtp
mnrksmpeadfsswtpleflvetfhdwitgnkrpnsgsliqvvttdgkteltpayf

Timeline for d1dird_:

• d1dird_ first appeared (with stable ids) in SCOP 1.55
  
• d1dird_ appears in SCOPe 2.05
  
• d1dird_ appears in SCOPe 2.07
  
• d1dird_ appears in the current release, SCOPe 2.08