SCOP 1.73: Domain d1sepa_: 1sep A:

Lineage for d1sepa_ (1sep A:)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Sepiapterin reductase [51767] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [51768] (3 PDB entries)

8. Domain d1sepa_: 1sep A: [29830]
   complexed with bio, nap

Details for d1sepa_

PDB Entry: 1sep, 1.95 Å

PDB Description: mouse sepiapterin reductase complexed with nadp and sepiapterin

PDB Compounds: (A:) sepiapterin reductase

SCOP Domain Sequences for d1sepa_:

Sequence; same for both SEQRES and ATOM records:

>d1sepa_ c.2.1.2 (A:) Sepiapterin reductase {Mouse (Mus musculus) [TaxId: 10090]}
adglgcavcvltgasrgfgralapqlarllspgsvmlvsarsesmlrqlkeelgaqqpdl
kvvlaaadlgteagvqrllsavrelprpeglqrlllinnaatlgdvskgflnvndlaevn
nywalnltsmlcltsgtlnafqdspglsktvvnisslcalqpykgwglycagkaardmly
qvlaaeepsvrvlsyapgpldndmqqlaretskdpelrsklqklksdgalvdcgtsaqkl
lgllqkdtfqsgahvdfyd

Timeline for d1sepa_:

• d1sepa_ first appeared (with stable ids) in SCOP 1.55, called d1sep__
  
• d1sepa_ was called d1sep__ in SCOP 1.71
  
• d1sepa_ appears in SCOP 1.75
  
• d1sepa_ appears in the current release, SCOPe 2.08