SCOPe 2.05: Domain d1e7sa_: 1e7s A:

Lineage for d1e7sa_ (1e7s A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein GDP-4-keto-6-deoxy-d-mannose epimerase/reductase (GDP-fucose synthetase) [51757] (1 species)

7. Species Escherichia coli [TaxId:562] [51758] (8 PDB entries)

8. Domain d1e7sa_: 1e7s A: [29806]
   complexed with nap, so4, trs, uvw

Details for d1e7sa_

PDB Entry: 1e7s, 1.5 Å

PDB Description: gdp 4-keto-6-deoxy-d-mannose epimerase reductase k140r

PDB Compounds: (A:) GDP-fucose synthetase

SCOPe Domain Sequences for d1e7sa_:

Sequence; same for both SEQRES and ATOM records:

>d1e7sa_ c.2.1.2 (A:) GDP-4-keto-6-deoxy-d-mannose epimerase/reductase (GDP-fucose synthetase) {Escherichia coli [TaxId: 562]}
kqrvfiaghrgmvgsairrqleqrgdvelvlrtrdelnlldsravhdffaseridqvyla
aakvggivanntypadfiyqnmmiesniihaahqndvnkllflgssciypklakqpmaes
ellqgtleptnepyaiariagiklcesynrqygrdyrsvmptnlygphdnfhpsnshvip
allrrfheataqsapdvvvwgsgtpmreflhvddmaaasihvmelahevwlentqpmlsh
invgtgvdctirelaqtiakvvgykgrvvfdaskpdgtprklldvtrlhqlgwyheisle
aglastyqwflenq

Timeline for d1e7sa_:

• d1e7sa_ first appeared (with stable ids) in SCOP 1.55
  
• d1e7sa_ appears in SCOPe 2.04
  
• d1e7sa_ appears in SCOPe 2.06
  
• d1e7sa_ appears in the current release, SCOPe 2.08