SCOPe 2.06: Domain d1bxka_: 1bxk A:

Lineage for d1bxka_ (1bxk A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein dTDP-glucose 4,6-dehydratase (RmlB) [51755] (4 species)

7. Species Escherichia coli [TaxId:562] [51756] (1 PDB entry)

8. Domain d1bxka_: 1bxk A: [29803]
   complexed with nad

Details for d1bxka_

PDB Entry: 1bxk, 1.9 Å

PDB Description: dtdp-glucose 4,6-dehydratase from e. coli

PDB Compounds: (A:) protein (dtdp-glucose 4,6-dehydratase)

SCOPe Domain Sequences for d1bxka_:

Sequence, based on SEQRES records:

>d1bxka_ c.2.1.2 (A:) dTDP-glucose 4,6-dehydratase (RmlB) {Escherichia coli [TaxId: 562]}
mrkilitggagfigsalvryiinetsdavvvvdkltyagnlmslapvaqserfafekvdi
cdraelarvftehqpdcvmhlaaeshvdrsidgpaafietnivgtytlleaaraywnalt
edkksafrfhhistdevygdlhstddfftettpyapsspysaskassdhlvrawlrtygl
ptlitncsnnygpyhfpekliplmilnalagkslpvygngqqirdwlyvedharalycva
ttgkvgetynigghnerknldvveticelleelapnkphgvahyrdlitfvadrpghdlr
yaidaskiarelgcvpqetfesgmrktvqwylaneswwkqvqdgsyqger

Sequence, based on observed residues (ATOM records):

>d1bxka_ c.2.1.2 (A:) dTDP-glucose 4,6-dehydratase (RmlB) {Escherichia coli [TaxId: 562]}
mrkilitggagfigsalvryiinetsdavvvvdkltyagnlmslapvaqserfafekvdi
cdraelarvftehqpdcvmhlaaeshvdrsidgpaafietnivgtytlleaaraywnalt
edkksafrfhhistdevygdlhstddfftettpyapsspysaskassdhlvrawlrtygl
ptlitncsnnygpyhfpekliplmilnalagkslpvygngqqirdwlyvedharalycva
ttgkvgetynigghnerknldvveticelleelapnkphgvahyrdlitfryaidaskia
relgcvpqetfesgmrktvqwylaneswwkqvqdgsyqger

Timeline for d1bxka_:

• d1bxka_ first appeared (with stable ids) in SCOP 1.55
  
• d1bxka_ appears in SCOPe 2.05
  
• d1bxka_ appears in SCOPe 2.07
  
• d1bxka_ appears in the current release, SCOPe 2.08