SCOP 1.63: Domain d1d1tc2: 1d1t C:175-324

Lineage for d1d1tc2 (1d1t C:175-324)

Root: SCOP 1.63
Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families)
Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain [51736] (6 proteins)
N-terminal all-beta domain defines family
Protein Alcohol dehydrogenase [51737] (5 species)
Species Human (Homo sapiens), different isozymes [TaxId:9606] [51739] (17 PDB entries)
Domain d1d1tc2: 1d1t C:175-324 [29737]
Other proteins in same PDB: d1d1ta1, d1d1tb1, d1d1tc1, d1d1td1

Details for d1d1tc2

PDB Entry: 1d1t (more details), 2.4 Å

PDB Description: mutant of human sigma alcohol dehydrogenase with leucine at position 141

SCOP Domain Sequences for d1d1tc2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1d1tc2 c.2.1.1 (C:175-324) Alcohol dehydrogenase {Human (Homo sapiens), different isozymes}
gfstgygaavktgkvkpgstcvvfglggvglsvimgcksagasriigidlnkdkfekama
vgatecispkdstkpisevlsemtgnnvgytfevighletmidalaschmnygtsvvvgv
ppsakmltydpmllftgrtwkgcvfgglks

SCOP Domain Coordinates for d1d1tc2:

Click to download the PDB-style file with coordinates for d1d1tc2.
(The format of our PDB-style files is described here.)

Timeline for d1d1tc2: