Lineage for d1a72a2 (1a72 A:164-339)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841006Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (19 proteins)
    N-terminal all-beta domain defines family
  6. 2841027Protein Alcohol dehydrogenase [51737] (9 species)
  7. 2841044Species Horse (Equus caballus) [TaxId:9796] [51738] (52 PDB entries)
    Uniprot P00327
  8. 2841140Domain d1a72a2: 1a72 A:164-339 [29715]
    Other proteins in same PDB: d1a72a1
    complexed with pad, zn; mutant

Details for d1a72a2

PDB Entry: 1a72 (more details), 2.6 Å

PDB Description: an active-site double mutant (phe93->trp, val203->ala) of horse liver alcohol dehydrogenase in complex with the isosteric nad analog cpad
PDB Compounds: (A:) horse liver alcohol dehydrogenase

SCOPe Domain Sequences for d1a72a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1a72a2 c.2.1.1 (A:164-339) Alcohol dehydrogenase {Horse (Equus caballus) [TaxId: 9796]}

SCOPe Domain Coordinates for d1a72a2:

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Timeline for d1a72a2:

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