SCOPe 2.07: Domain d1eyea_: 1eye A:

Lineage for d1eyea_ (1eye A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.21: Dihydropteroate synthetase-like [51717] (3 families)

5. Family c.1.21.1: Dihydropteroate synthetase [51718] (2 proteins)

6. Protein Dihydropteroate synthetase [51719] (5 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [51722] (1 PDB entry)

8. Domain d1eyea_: 1eye A: [29672]
   complexed with mg, pmm

Details for d1eyea_

PDB Entry: 1eye, 1.7 Å

PDB Description: 1.7 angstrom resolution crystal structure of 6-hydroxymethyl-7,8- dihydropteroate synthase (dhps) from mycobacterium tuberculosis in complex with 6-hydroxymethylpterin monophosphate

PDB Compounds: (A:) dihydropteroate synthase I

SCOPe Domain Sequences for d1eyea_:

Sequence, based on SEQRES records:

>d1eyea_ c.1.21.1 (A:) Dihydropteroate synthetase {Mycobacterium tuberculosis [TaxId: 1773]}
pvqvmgvlnvtddsfsdggcyldlddavkhglamaaagagivdvggessrpgatrvdpav
etsrvipvvkelaaqgitvsidtmradvaraalqngaqmvndvsggradpamgpllaead
vpwvlmhwravsadtphvpvrygnvvaevradllasvadavaagvdparlvldpglgfak
taqhnwailhalpelvatgipvlvgasrkrflgallagpdgvmrptdgrdtatavisala
alhgawgvrvhdvrasvdaikvveawmgae

Sequence, based on observed residues (ATOM records):

>d1eyea_ c.1.21.1 (A:) Dihydropteroate synthetase {Mycobacterium tuberculosis [TaxId: 1773]}
pvqvmgvlnvtddsfsdggcyldlddavkhglamaaagagivdvggetsrvipvvkelaa
qgitvsidtmradvaraalqngaqmvndvsggradpamgpllaeadvpwvlmhwravsad
tphvpvrygnvvaevradllasvadavaagvdparlvldpglgfaktaqhnwailhalpe
lvatgipvlvgasrkrflgallagpdgvmrptdgrdtatavisalaalhgawgvrvhdvr
asvdaikvveawmgae

Timeline for d1eyea_:

• d1eyea_ first appeared (with stable ids) in SCOP 1.55
  
• d1eyea_ appears in SCOPe 2.06
  
• d1eyea_ appears in the current release, SCOPe 2.08