SCOPe 2.08: Domain d3r4oa2: 3r4o A:226-226

Lineage for d3r4oa2 (3r4o A:226-226)

1. Root: SCOPe 2.08

2. Class l: Artifacts [310555] (1 fold)

3. Fold l.1: Tags [310573] (1 superfamily)

4. Superfamily l.1.1: Tags [310607] (1 family)

5. Family l.1.1.1: Tags [310682] (2 proteins)

6. Protein C-terminal Tags [310895] (1 species)

7. Species Synthetic [311502] (6039 PDB entries)

8. Domain d3r4oa2: 3r4o A:226-226 [294932]
   Other proteins in same PDB: d3r4oa1, d3r4ob1
   complexed with fu3

Details for d3r4oa2

PDB Entry: 3r4o, 2.65 Å

PDB Description: Optimization of Potent, Selective, and Orally Bioavailable Pyrrolodinopyrimidine-containing Inhibitors of Heat Shock Protein 90. Identification of Development Candidate 2-amino-4-{4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl}-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide

PDB Compounds: (A:) Heat shock protein HSP 90-alpha

SCOPe Domain Sequences for d3r4oa2:

Sequence; same for both SEQRES and ATOM records:

>d3r4oa2 l.1.1.1 (A:226-226) C-terminal Tags {Synthetic}
l

Timeline for d3r4oa2:

• d3r4oa2 first appeared in SCOPe 2.06
  
• d3r4oa2 appears in SCOPe 2.07