SCOPe 2.02: Domain d1f8mc_: 1f8m C:

Lineage for d1f8mc_ (1f8m C:)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families)

5. Family c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like [88704] (4 proteins)
   forms a swapped dimer

6. Protein Isocitrate lyase [51642] (3 species)
   elaborated with additional subdomains

7. Species Mycobacterium tuberculosis [TaxId:1773] [51644] (3 PDB entries)

8. Domain d1f8mc_: 1f8m C: [29317]
   complexed with mg, pyr

Details for d1f8mc_

PDB Entry: 1f8m, 1.8 Å

PDB Description: crystal structure of 3-bromopyruvate modified isocitrate lyase (icl) from mycobacterium tuberculosis

PDB Compounds: (C:) isocitrate lyase

SCOPe Domain Sequences for d1f8mc_:

Sequence; same for both SEQRES and ATOM records:

>d1f8mc_ c.1.12.7 (C:) Isocitrate lyase {Mycobacterium tuberculosis [TaxId: 1773]}
asvvgtpksaeqiqqewdtnprwkdvtrtysaedvvalqgsvveehtlarrgaevlweql
hdlewvnalgaltgnmavqqvraglkaiylsgwqvagdanlsghtypdqslypansvpqv
vrrinnalqradqiakiegdtsvenwlapivadgeagfggalnvyelqkaliaagvagsh
wedqlasekkcghlggkvliptqqhirtltsarlaadvadvptvviartdaeaatlitsd
vderdqpfitgertregfyrtkngiepciarakayapfadliwmetgtpdleaarqfsea
vkaeypdqmlayncspsfnwkkhlddatiakfqkelaamgfkfqfitlagfhalnysmfd
laygyaqnqmsayvelqerefaaeergytatkhqrevgagyfdriattvdpnssttaltg
steegqf

Timeline for d1f8mc_:

• d1f8mc_ first appeared (with stable ids) in SCOP 1.55
  
• d1f8mc_ appears in SCOPe 2.01
  
• d1f8mc_ appears in SCOPe 2.03
  
• d1f8mc_ appears in the current release, SCOPe 2.08