SCOP 1.73: Domain d1a3wb2: 1a3w B:2-87,B:189-366

Lineage for d1a3wb2 (1a3w B:2-87,B:189-366)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (6 families)

5. Family c.1.12.1: Pyruvate kinase [51622] (1 protein)

6. Protein Pyruvate kinase, N-terminal domain [51623] (6 species)
   this domain is interrupted by an all-beta domain
   C-terminal domain is alpha/beta

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51627] (2 PDB entries)

8. Domain d1a3wb2: 1a3w B:2-87,B:189-366 [29289]
   Other proteins in same PDB: d1a3wa1, d1a3wa3, d1a3wb1, d1a3wb3
   complexed with fbp, k, mn, pga

Details for d1a3wb2

PDB Entry: 1a3w, 3 Å

PDB Description: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg, mn2+ and k+

PDB Compounds: (B:) pyruvate kinase

SCOP Domain Sequences for d1a3wb2:

Sequence, based on SEQRES records:

>d1a3wb2 c.1.12.1 (B:2-87,B:189-366) Pyruvate kinase, N-terminal domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
srlerltslnvvagsdlrrtsiigtigpktnnpetlvalrkaglnivrmnfshgsyeyhk
svidnarkseelypgrplaialdtkgXpalsekdkedlrfgvkngvhmvfasfirtandv
ltirevlgeqgkdvkiivkienqqgvnnfdeilkvtdgvmvargdlgieipapevlavqk
kliaksnlagkpvicatqmlesmtynprptraevsdvgnaildgadcvmlsgetakgnyp
inavttmaetaviaeqaiaylpnyd

Sequence, based on observed residues (ATOM records):

>d1a3wb2 c.1.12.1 (B:2-87,B:189-366) Pyruvate kinase, N-terminal domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
srlerltslsdlrrtsiigtigpktnnpetlvalrkaglnivrmnfshgsyeyhksvidn
arkseelypgrplaialdtkgXpalsekdkedlrfgvkngvhmvfasfirtandvltire
vlgeqgkdvkiivkienqqgvnnfdeilkvtdgvmvargdlgieipapevlavqkkliak
snlagkpvicatqmlesmtynprptraevsdvgnaildgadcvmlsgetakgnypinavt
tmaetaviaeqaiaylpnyd

Timeline for d1a3wb2:

• d1a3wb2 first appeared (with stable ids) in SCOP 1.55
  
• d1a3wb2 appears in SCOP 1.71
  
• d1a3wb2 appears in SCOP 1.75
  
• d1a3wb2 appears in the current release, SCOPe 2.08