SCOP 1.69: Domain d1pkn_2: 1pkn 12-115,218-395

Lineage for d1pkn_2 (1pkn 12-115,218-395)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (31 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (6 families)

5. Family c.1.12.1: Pyruvate kinase [51622] (1 protein)

6. Protein Pyruvate kinase, N-terminal domain [51623] (6 species)
   this domain is interrupted by an all-beta domain
   C-terminal domain is alpha/beta

7. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [51625] (6 PDB entries)

8. Domain d1pkn_2: 1pkn 12-115,218-395 [29271]
   Other proteins in same PDB: d1pkn_1, d1pkn_3

Details for d1pkn_2

PDB Entry: 1pkn, 2.9 Å

PDB Description: structure of rabbit muscle pyruvate kinase complexed with mn2+, k+, and pyruvate

SCOP Domain Sequences for d1pkn_2:

Sequence; same for both SEQRES and ATOM records:

>d1pkn_2 c.1.12.1 (12-115,218-395) Pyruvate kinase, N-terminal domain {Rabbit (Oryctolagus cuniculus)}
iqtqqlhaamadtflehmcrldidsapitarntgiictigpasrsvetlkemiksgmnva
rmnfshgtheyhaetiknvrtatesfasdpilyrpvavaldtkgXpavsekdiqdlkfgv
dedvdmvfasfirkaadvhevrkilgekgknikiiskienhegvrrfdeileasdgimva
rgdlgieipaekvflaqkmiigrcnragkpvicatqmlesmikkprptraegsdvanavl
dgadcimlsgetakgdypleavrmqhliareaeaamfhrklfe

Timeline for d1pkn_2:

• d1pkn_2 first appeared (with stable ids) in SCOP 1.55
  
• d1pkn_2 appears in SCOP 1.67
  
• d1pkn_2 appears in SCOP 1.71
  
• d1pkn_2 appears in the current release, SCOPe 2.08, called d1pkna2