SCOPe 2.08: Domain d1aw5a_: 1aw5 A:

Lineage for d1aw5a_ (1aw5 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (2 proteins)
   hybrid of classes I and II aldolase
   automatically mapped to Pfam PF00490

6. Protein 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51595] (5 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51596] (12 PDB entries)

8. Domain d1aw5a_: 1aw5 A: [29181]
   complexed with zn

Details for d1aw5a_

PDB Entry: 1aw5, 2.3 Å

PDB Description: 5-aminolevulinate dehydratase from saccharomyces cerevisiae

PDB Compounds: (A:) 5-aminolevulinate dehydratase

SCOPe Domain Sequences for d1aw5a_:

Sequence, based on SEQRES records:

>d1aw5a_ c.1.10.3 (A:) 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mhtaefletepteissvlaggynhpllrqwqserqltknmlifplfisdnpddfteidsa
pninrigvnrlkdylkplvakglrsvilfgvplipgtkdpvgtaaddpagpviqgirfir
ekfpelyiicdvclceytshghcgvlyddgtinrersvsrlaavavnyakagahcvapsd
midgrirdikrglinanlahktfvlsyaakfsgnlygpardaacsapsngdrkcyqlppa
grglarralerdmsegadgiivkpstfyldivrdaseickdlpicayhvsgeyamlhaaa
ekgvvdlktiafeshqgflragarliitylapefldwlde

Sequence, based on observed residues (ATOM records):

>d1aw5a_ c.1.10.3 (A:) 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mhtaefletepteissvlaggynhpllrqwqserqltknmlifplfisdnpddfteidsa
pninrigvnrlkdylkplvakglrsvilfgvplipgtkdpvgtaaddpagpviqgirfir
ekfpelyiicdvclceytshghcgvlyddgtinrersvsrlaavavnyakagahcvapsd
midgrirdikrglinanlahktfvlsyaakfsgnlygpacyqlppagrglarralerdms
egadgiivkpstfyldivrdaseickdlpicayhvsgeyamlhaaaekgvvdlktiafes
hqgflragarliitylapefldwlde

Timeline for d1aw5a_:

• d1aw5a_ first appeared (with stable ids) in SCOP 1.55, called d1aw5__
  
• d1aw5a_ appears in SCOPe 2.07