SCOPe 2.06: Domain d1alda_: 1ald A:

Lineage for d1alda_ (1ald A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (13 proteins)
   the catalytic lysine forms schiff-base intermediate with substrate
   possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein Fructose-1,6-bisphosphate aldolase [51576] (11 species)

7. Species Human (Homo sapiens), muscle isozyme [TaxId:9606] [51577] (4 PDB entries)

8. Domain d1alda_: 1ald A: [29100]

Details for d1alda_

PDB Entry: 1ald, 2 Å

PDB Description: activity and specificity of human aldolases

PDB Compounds: (A:) aldolase a

SCOPe Domain Sequences for d1alda_:

Sequence; same for both SEQRES and ATOM records:

>d1alda_ c.1.10.1 (A:) Fructose-1,6-bisphosphate aldolase {Human (Homo sapiens), muscle isozyme [TaxId: 9606]}
pyqypaltpeqkkelsdiahrivapgkgilaadestgsiakrlqsigtenteenrrfyrq
llltaddrvnpciggvilfhetlyqkaddgrpfpqvikskggvvgikvdkgvvplagtng
etttqgldglsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqqn
givpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghact
qkfsheeiamatvtalrrtvppavtgitflsggqseeeasinlnainkcpllkpwaltfs
ygralqasalkawggkkenlkaaqeeyvkralanslacqgkytpsgqagaaaseslfvsn
hay

Timeline for d1alda_:

• d1alda_ first appeared (with stable ids) in SCOP 1.55, called d1ald__
  
• d1alda_ appears in SCOPe 2.05
  
• d1alda_ appears in SCOPe 2.07
  
• d1alda_ appears in the current release, SCOPe 2.08