SCOP 1.73: Domain d1f73c_: 1f73 C:

Lineage for d1f73c_ (1f73 C:)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (8 families)
   Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (12 proteins)
   the catalytic lysine forms schiff-base intermediate with substrate
   possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein N-acetylneuraminate lyase [51571] (2 species)

7. Species Haemophilus influenzae [TaxId:727] [51573] (6 PDB entries)

8. Domain d1f73c_: 1f73 C: [29091]

Details for d1f73c_

PDB Entry: 1f73, 1.95 Å

PDB Description: crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form iii in complex with sialic acid alditol

PDB Compounds: (C:) n-acetyl neuraminate lyase

SCOP Domain Sequences for d1f73c_:

Sequence, based on SEQRES records:

>d1f73c_ c.1.10.1 (C:) N-acetylneuraminate lyase {Haemophilus influenzae [TaxId: 727]}
mrdlkgifsallvsfnedgtinekglrqiirhnidkmkvdglyvggstgenfmlsteekk
eifriakdeakdqialiaqvgsvnlkeavelgkyatelgydclsavtpfyykfsfpeikh
yydtiiaetgsnmivysipfltgvnmgieqfgelyknpkvlgvkftagdfyllerlkkay
pnhliwagfdemmlpaaslgvdgaigstfnvngvrarqifeltkagklkealeiqhvtnd
liegilanglyltikellklegvdagycrepmtskataeqvakakdlkakfls

Sequence, based on observed residues (ATOM records):

>d1f73c_ c.1.10.1 (C:) N-acetylneuraminate lyase {Haemophilus influenzae [TaxId: 727]}
mrdlkgifsallvsfnedgtinekglrqiirhnidkmkvdglyvggstgenfmlsteekk
eifriakdeakdqialiaqvgsvnlkeavelgkyatelgydclsavtpfyykfsfpeikh
yydtiiaetgsnmivysipnmgieqfgelyknpkvlgvkftagdfyllerlkkaypnhli
wagfdemmlpaaslgvdgaigstfnvngvrarqifeltkagklkealeiqhvtndliegi
langlyltikellklegvdagycrepmtskataeqvakakdlkakfls

Timeline for d1f73c_:

• d1f73c_ first appeared (with stable ids) in SCOP 1.55
  
• d1f73c_ appears in SCOP 1.71
  
• d1f73c_ appears in SCOP 1.75
  
• d1f73c_ appears in the current release, SCOPe 2.08