SCOP 1.65: Domain d1fwhc2: 1fwh C:130-422,C:476-567

Lineage for d1fwhc2 (1fwh C:130-422,C:476-567)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (26 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (13 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.2: alpha-subunit of urease, catalytic domain [51560] (1 protein)

6. Protein alpha-subunit of urease, catalytic domain [51561] (3 species)

7. Species Klebsiella aerogenes [TaxId:28451] [51562] (26 PDB entries)

8. Domain d1fwhc2: 1fwh C:130-422,C:476-567 [29036]
   Other proteins in same PDB: d1fwha_, d1fwhb_, d1fwhc1
   complexed with ni; mutant

Details for d1fwhc2

PDB Entry: 1fwh, 2 Å

PDB Description: klebsiella aerogenes urease, c319y variant

SCOP Domain Sequences for d1fwhc2:

Sequence; same for both SEQRES and ATOM records:

>d1fwhc2 c.1.9.2 (C:130-422,C:476-567) alpha-subunit of urease, catalytic domain {Klebsiella aerogenes}
gidthihwicpqqaeealvsgvttmvgggtgpaagthattctpgpwyisrmlqaadslpv
nigllgkgnvsqpdalreqvaagviglkihedwgatpaaidcaltvademdiqvalhsdt
lnesgfvedtlaaiggrtihtfhtegaggghapdiitacahpnilpsstnptlpytlnti
dehldmlmvyhhldpdiaedvafaesrirretiaaedvlhdlgafsltssdsqamgrvge
vilrtwqvahrmkvqrgalaeetgdndnfrvkryiakytinpalthgiahevgXmfgalg
sarhhcrltflsqaaaangvaerlnlrsaiavvkgcrtvqkadmvhnslqpnitvdaqty
evrvdgelitsepadvlpmaqryflf

Timeline for d1fwhc2:

• d1fwhc2 first appeared (with stable ids) in SCOP 1.55
  
• d1fwhc2 appears in SCOP 1.63
  
• d1fwhc2 appears in SCOP 1.67
  
• d1fwhc2 appears in the current release, SCOPe 2.08