SCOPe 2.08: Domain d1fwic2: 1fwi C:130-422,C:476-567

Lineage for d1fwic2 (1fwi C:130-422,C:476-567)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (19 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.2: alpha-subunit of urease, catalytic domain [51560] (1 protein)

6. Protein alpha-subunit of urease, catalytic domain [51561] (4 species)

7. Species Klebsiella aerogenes [TaxId:28451] [51562] (28 PDB entries)

8. Domain d1fwic2: 1fwi C:130-422,C:476-567 [29029]
   Other proteins in same PDB: d1fwia_, d1fwib_, d1fwic1
   complexed with ni

Details for d1fwic2

PDB Entry: 1fwi, 2 Å

PDB Description: klebsiella aerogenes urease, h134a variant

PDB Compounds: (C:) urease

SCOPe Domain Sequences for d1fwic2:

Sequence, based on SEQRES records:

>d1fwic2 c.1.9.2 (C:130-422,C:476-567) alpha-subunit of urease, catalytic domain {Klebsiella aerogenes [TaxId: 28451]}
gidtaihwicpqqaeealvsgvttmvgggtgpaagthattctpgpwyisrmlqaadslpv
nigllgkgnvsqpdalreqvaagviglkihedwgatpaaidcaltvademdiqvalhsdt
lnesgfvedtlaaiggrtihtfhtegaggghapdiitacahpnilpsstnptlpytlnti
dehldmlmvchhldpdiaedvafaesrirretiaaedvlhdlgafsltssdsqamgrvge
vilrtwqvahrmkvqrgalaeetgdndnfrvkryiakytinpalthgiahevgXmfgalg
sarhhcrltflsqaaaangvaerlnlrsaiavvkgcrtvqkadmvhnslqpnitvdaqty
evrvdgelitsepadvlpmaqryflf

Sequence, based on observed residues (ATOM records):

>d1fwic2 c.1.9.2 (C:130-422,C:476-567) alpha-subunit of urease, catalytic domain {Klebsiella aerogenes [TaxId: 28451]}
gidtaihwicpqqaeealvsgvttmvgggtgpaagthattctpgpwyisrmlqaadslpv
nigllgkgnvsqpdalreqvaagviglkihedwgatpaaidcaltvademdiqvalhsdt
lnesgfvedtlaaiggrtihtfhtegaggghapdiitacahpnilpsstnptlpytlnti
dehldmlfaesrirretiaaedvlhdlgafsltssdsqamgrvgevilrtwqvahrmkvq
rgalaeetgdndnfrvkryiakytinpalthgiahevgXmfgalgsarhhcrltflsqaa
aangvaerlnlrsaiavvkgcrtvqkadmvhnslqpnitvdaqtyevrvdgelitsepad
vlpmaqryflf

Timeline for d1fwic2:

• d1fwic2 first appeared (with stable ids) in SCOP 1.55
  
• d1fwic2 appears in SCOPe 2.07