SCOPe 2.04: Domain d2cxga4: 2cxg A:1-406

Lineage for d2cxga4 (2cxg A:1-406)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (15 families)

5. Family c.1.8.1: Amylase, catalytic domain [51446] (26 proteins)
   members of the family may contain various insert subdomains
   in alpha-amylases and closer relatives this domain is usually followed by a common all-beta domain

6. Protein Cyclodextrin glycosyltransferase [51452] (5 species)
   contains two more all-beta domains, one is Immunoglobulin-like and the other is trasthyretin-like

7. Species Bacillus circulans, different strains [TaxId:1397] [51453] (36 PDB entries)

8. Domain d2cxga4: 2cxg A:1-406 [28733]
   Other proteins in same PDB: d2cxga1, d2cxga2, d2cxga3
   complexed with ca

Details for d2cxga4

PDB Entry: 2cxg, 2.5 Å

PDB Description: cyclodextrin glycosyltransferase complexed to the inhibitor acarbose

PDB Compounds: (A:) cyclodextrin glycosyltransferase

SCOPe Domain Sequences for d2cxga4:

Sequence; same for both SEQRES and ATOM records:

>d2cxga4 c.1.8.1 (A:1-406) Cyclodextrin glycosyltransferase {Bacillus circulans, different strains [TaxId: 1397]}
apdtsvsnkqnfstdviyqiftdrfsdgnpannptgaafdgtctnlrlycggdwqgiink
indgyltgmgvtaiwisqpveniysiinysgvnntayhgywardfkktnpaygtiadfqn
liaaahaknikviidfapnhtspassdqpsfaengrlydngtllggytndtqnlfhhngg
tdfsttengiyknlydladlnhnnstvdvylkdaikmwldlgidgirmdavkhmpfgwqk
sfmaavnnykpvftfgewflgvnevspenhkfanesgmslldfrfaqkvrqvfrdntdnm
yglkamlegsaadyaqvddqvtfidnhdmerfhasnanrrkleqalaftltsrgvpaiyy
gteqymsggtdpdnraripsfststtayqviqklaplrkcnpaiay

Timeline for d2cxga4:

• d2cxga4 first appeared (with stable ids) in SCOP 1.55, called d2cxg_4
  
• d2cxga4 appears in SCOPe 2.03
  
• d2cxga4 appears in SCOPe 2.05
  
• d2cxga4 appears in the current release, SCOPe 2.08