SCOP 1.73: Domain d1lwia_: 1lwi A:

Lineage for d1lwia_ (1lwi A:)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (1 family)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (15 proteins)
   Common fold covers whole protein structure

6. Protein 3-alpha-hydroxysteroid dehydrogenase [51439] (2 species)

7. Species Rat (Rattus norvegicus) [TaxId:10116] [51440] (3 PDB entries)

8. Domain d1lwia_: 1lwi A: [28696]

Details for d1lwia_

PDB Entry: 1lwi, 2.7 Å

PDB Description: 3-alpha-hydroxysteroid/dihydrodiol dehydrogenase from rattus norvegicus

PDB Compounds: (A:) 3-alpha-hydroxysteroid/dihydrodiol dehydrogenase

SCOP Domain Sequences for d1lwia_:

Sequence, based on SEQRES records:

>d1lwia_ c.1.7.1 (A:) 3-alpha-hydroxysteroid dehydrogenase {Rat (Rattus norvegicus) [TaxId: 10116]}
mdsislrvalndgnfipvlgfgttvpekvakdevikatkiaidngfrhfdsaylyeveee
vgqairskiedgtvkredifytsklwstfhrpelvrtclektlkstqldyvdlyiihfpm
alqpgdiffprdehgkllfetvdicdtweamekckdaglaksigvsnfncrqlerilnkp
glkykpvcnqvechlylnqskmldyckskdiilvsyctlgssrdktwvdqkspvllddpv
lcaiakkykqtpalvalryqlqrgvvplirsfnakrikeltqvfefqlasedmkaldgln
rnfrynnakyf

Sequence, based on observed residues (ATOM records):

>d1lwia_ c.1.7.1 (A:) 3-alpha-hydroxysteroid dehydrogenase {Rat (Rattus norvegicus) [TaxId: 10116]}
mdsislrvalndgnfipvlgfgttvpakdevikatkiaidngfrhfdsaylyeveeevgq
airskiedgtvkredifytsklwstfhrpelvrtclektlkstqldyvdlyiihfpmalq
pgdiffprdehgkllfetvdicdtweamekckdaglaksigvsnfncrqlerilnkpglk
ykpvcnqvechlylnqskmldyckskdiilvsyctlgsktwvdqkspvllddpvlcaiak
kykqtpalvalryqlqrgvvplirsfnakrikeltqvfefqlasedmkaldglnrnfryn
nakyf

Timeline for d1lwia_:

• d1lwia_ first appeared (with stable ids) in SCOP 1.55
  
• d1lwia_ appears in SCOP 1.71
  
• d1lwia_ appears in SCOP 1.75
  
• d1lwia_ appears in the current release, SCOPe 2.08