SCOP 1.65: Domain d1dlaa_: 1dla A:

Lineage for d1dlaa_ (1dla A:)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (26 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (1 family)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (10 proteins)
   Common fold covers whole protein structure

6. Protein Aldose reductase (aldehyde reductase) [51436] (2 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [51438] (8 PDB entries)

8. Domain d1dlaa_: 1dla A: [28690]

Details for d1dlaa_

PDB Entry: 1dla, 3 Å

PDB Description: novel nadph-binding domain revealed by the crystal structure of aldose reductase

SCOP Domain Sequences for d1dlaa_:

Sequence, based on SEQRES records:

>d1dlaa_ c.1.7.1 (A:) Aldose reductase (aldehyde reductase) {Pig (Sus scrofa)}
shlvlytgakmpilglgtwksppgkvteavkvaidlgyrhidcahvyqnenevglglqek
lqgqvvkredlfivsklwctdheknlvkgacqttlrdlkldyldlylihwptgfkpgkdp
fpldgdgnvvpdesdfvetweameelvdeglvkaigvsnfnhlqvekilnkpglkykpav
nqievhpyltqeklieyckskgivvtaysplgspdrpwakpedpslledprikaiaakyn
kttaqvlirfpmqrnlivipksvtperiaenfqvfdfelspedmntllsynrnwrvcalm
scashkdypfheey

Sequence, based on observed residues (ATOM records):

>d1dlaa_ c.1.7.1 (A:) Aldose reductase (aldehyde reductase) {Pig (Sus scrofa)}
shlvlytgakmpilglgtwksppgkvteavkvaidlgyrhidcahvyqnenevglglqek
lqgqvvkredlfivsklwctdheknlvkgacqttlrdlkldyldlylihwptgfkpgkdp
fpldgdgnvvpdesdfvetweameelvdeglvkaigvsnfnhlqvekilnkpglkykpav
nqievhpyltqeklieyckskgivvtaysplgspdrpwaslledprikaiaakynkttaq
vlirfpmqrnlivipksvtperiaenfqvfdfelspedmntllsynrnwrvcalmscash
kdypfheey

Timeline for d1dlaa_:

• d1dlaa_ first appeared (with stable ids) in SCOP 1.55
  
• d1dlaa_ appears in SCOP 1.63
  
• d1dlaa_ appears in SCOP 1.67
  
• d1dlaa_ appears in the current release, SCOPe 2.08