SCOP 1.73: Domain d1ak5a1: 1ak5 A:2-101,A:222-483

Lineage for d1ak5a1 (1ak5 A:2-101,A:222-483)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (1 family)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein)

6. Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (6 species)

7. Species Tritrichomonas foetus [TaxId:5724] [51417] (9 PDB entries)

8. Domain d1ak5a1: 1ak5 A:2-101,A:222-483 [28639]
   there two CBS domains in the disordered region 102-221
   complexed with so4

Details for d1ak5a1

PDB Entry: 1ak5, 2.3 Å

PDB Description: inosine monophosphate dehydrogenase (impdh) from tritrichomonas foetus

PDB Compounds: (A:) inosine-5'-monophosphate dehydrogenase

SCOP Domain Sequences for d1ak5a1:

Sequence, based on SEQRES records:

>d1ak5a1 c.1.5.1 (A:2-101,A:222-483) Inosine monophosphate dehydrogenase (IMPDH) {Tritrichomonas foetus [TaxId: 5724]}
akyynepchtfneyllipglstvdcipsnvnlstplvkfqkgqqseinlkiplvsaimqs
vsgekmaialareggisfifgsqsiesqaamvhavknfkaXhnelvdsqkrylvgagint
rdfrervpalveagadvlcidssdgfsewqkitigwirekygdkvkvgagnivdgegfry
ladagadfikigigggsicitreqkgigrgqatavidvvaernkyfeetgiyipvcsdgg
ivydyhmtlalamgadfimlgryfarfeesptrkvtingsvmkeywgegssrarnwqryd
lggkqklsfeegvdsyvpyagklkdnveaslnkvkstmcncgaltipqlqskakitlvss
vsi

Sequence, based on observed residues (ATOM records):

>d1ak5a1 c.1.5.1 (A:2-101,A:222-483) Inosine monophosphate dehydrogenase (IMPDH) {Tritrichomonas foetus [TaxId: 5724]}
akyynepchtfneyllipglstvdcipsnvnlstplvkfqkgqqseinlkiplvsaimqs
vsgekmaialareggisfifgsqsiesqaamvhavknfkaXhnelvdsqkrylvgagint
rdfrervpalveagadvlcidssdgfsewqkitigwirekygdkvkvgagnivdgegfry
ladagadfikigigrgqatavidvvaernkyfeetgiyipvcsdggivydyhmtlalamg
adfimlgryfarfeesptrkvtingsvmkeywgegssrgvdsyvpyagklkdnveaslnk
vkstmcncgaltipqlqskakitlvssvsi

Timeline for d1ak5a1:

• d1ak5a1 first appeared (with stable ids) in SCOP 1.55, called d1ak5_1
  
• d1ak5a1 was called d1ak5_1 in SCOP 1.71
  
• d1ak5a1 appears in SCOP 1.75
  
• d1ak5a1 appears in the current release, SCOPe 2.08