SCOP 1.75: Domain d1a50a_: 1a50 A:

Lineage for d1a50a_ (1a50 A:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (6 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (3 proteins)

6. Protein Trp synthase alpha-subunit [51388] (5 species)

7. Species Salmonella typhimurium [TaxId:90371] [51389] (49 PDB entries)

8. Domain d1a50a_: 1a50 A: [28580]
   Other proteins in same PDB: d1a50b_
   complexed with fip, na, plp

Details for d1a50a_

PDB Entry: 1a50, 2.3 Å

PDB Description: crystal structure of wild-type tryptophan synthase complexed with 5-fluoroindole propanol phosphate

PDB Compounds: (A:) tryptophan synthase (alpha chain)

SCOP Domain Sequences for d1a50a_:

Sequence, based on SEQRES records:

>d1a50a_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
eryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdpladg
ptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceqv
gvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrsg
vtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkii
eknlaspkqmlaelrsfvsamkaasr

Sequence, based on observed residues (ATOM records):

>d1a50a_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
eryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdpladg
ptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceqv
gvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrsg
vtgaenhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiieknlas
pkqmlaelrsfvsamkaasr

Timeline for d1a50a_:

• d1a50a_ first appeared (with stable ids) in SCOP 1.55
  
• d1a50a_ appears in SCOP 1.73
  
• d1a50a_ appears in SCOPe 2.01
  
• d1a50a_ appears in the current release, SCOPe 2.08