SCOP 1.75: Domain d1cw2a_: 1cw2 A:

Lineage for d1cw2a_ (1cw2 A:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (6 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (3 proteins)

6. Protein Trp synthase alpha-subunit [51388] (5 species)

7. Species Salmonella typhimurium [TaxId:90371] [51389] (49 PDB entries)

8. Domain d1cw2a_: 1cw2 A: [28578]
   Other proteins in same PDB: d1cw2b_

Details for d1cw2a_

PDB Entry: 1cw2, 2 Å

PDB Description: crystal structure of the complex of bacterial tryptophan synthase with the transition state analogue inhibitor 4-(2-hydroxyphenylsulfinyl)-butylphosphonic acid

PDB Compounds: (A:) tryptophan synthase (alpha chain)

SCOP Domain Sequences for d1cw2a_:

Sequence, based on SEQRES records:

>d1cw2a_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
eryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdpladg
ptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceqv
gvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrsg
vtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkii
eknlaspkqmlaelrsfvsamkaasr

Sequence, based on observed residues (ATOM records):

>d1cw2a_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
eryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdpladg
ptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceqv
gvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrsg
vtgaenrgplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiiek
nlaspkqmlaelrsfvsamkaasr

Timeline for d1cw2a_:

• d1cw2a_ first appeared (with stable ids) in SCOP 1.55
  
• d1cw2a_ appears in SCOP 1.73
  
• d1cw2a_ appears in SCOPe 2.01
  
• d1cw2a_ appears in the current release, SCOPe 2.08