SCOPe 2.05: Domain d1vdeb1: 1vde B:1-180,B:416-454

Lineage for d1vdeb1 (1vde B:1-180,B:416-454)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.86: Hedgehog/intein (Hint) domain [51293] (1 superfamily)
   complex fold made of five beta-hairpin units and a b-ribbon arc

4. Superfamily b.86.1: Hedgehog/intein (Hint) domain [51294] (3 families)
   duplication: contains two intertwined structural repeats

5. Family b.86.1.2: Intein (protein splicing domain) [51298] (5 proteins)

6. Protein VMA1-derived endonuclease (VDE) PI-Scei intein [51299] (1 species)
   also contains a homing endonuclease and DNA-binding domains

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51300] (8 PDB entries)
   Uniprot P17255 284-737

8. Domain d1vdeb1: 1vde B:1-180,B:416-454 [28379]
   Other proteins in same PDB: d1vdea2, d1vdea3, d1vdeb2, d1vdeb3

Details for d1vdeb1

PDB Entry: 1vde, 2.4 Å

PDB Description: pi-scei, a homing endonuclease with protein splicing activity

PDB Compounds: (B:) pi-scei

SCOPe Domain Sequences for d1vdeb1:

Sequence, based on SEQRES records:

>d1vdeb1 b.86.1.2 (B:1-180,B:416-454) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
cfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksqhrahk
sdssrevpellkftcnathelvvrtprsvrrlsrtikgveyfevitfemgqkkapdgriv
elvkevsksypisegperanelvesyrkasnkayfewtieardlsllgshvrkatyqtya
Xcrgfyfelqelkeddyygitlsddsdhqfllanqvvvhn

Sequence, based on observed residues (ATOM records):

>d1vdeb1 b.86.1.2 (B:1-180,B:416-454) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
cfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksqhrahk
sdssrevpellkftcnathelvvrtprsvrrlevitfemgqkkapdgrivelvkevsksy
pisegperanelvesyrkasnkayfewtieardlsllgshvrkatyqtyaXcrgfyfelq
elkeddyygitlsddsdhqfllanqvvvhn

Timeline for d1vdeb1:

• d1vdeb1 first appeared (with stable ids) in SCOP 1.55
  
• d1vdeb1 appears in SCOPe 2.04
  
• d1vdeb1 appears in SCOPe 2.06
  
• d1vdeb1 appears in the current release, SCOPe 2.08