SCOP 1.67: Domain d1vdea1: 1vde A:1-180,A:416-454

Lineage for d1vdea1 (1vde A:1-180,A:416-454)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.86: Hedgehog/intein (Hint) domain [51293] (1 superfamily)
   complex fold made of five beta-hairpin units and a b-ribbon arc

4. Superfamily b.86.1: Hedgehog/intein (Hint) domain [51294] (2 families)
   duplication: contains two intertwined structural repeats

5. Family b.86.1.2: Intein (protein splicing domain) [51298] (4 proteins)

6. Protein VMA1-derived endonuclease (VDE) PI-Scei intein [51299] (1 species)
   also contains a homing endonuclease and DNA-binding domains

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51300] (7 PDB entries)

8. Domain d1vdea1: 1vde A:1-180,A:416-454 [28378]
   Other proteins in same PDB: d1vdea2, d1vdea3, d1vdeb2, d1vdeb3

Details for d1vdea1

PDB Entry: 1vde, 2.4 Å

PDB Description: pi-scei, a homing endonuclease with protein splicing activity

SCOP Domain Sequences for d1vdea1:

Sequence, based on SEQRES records:

>d1vdea1 b.86.1.2 (A:1-180,A:416-454) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae)}
cfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksqhrahk
sdssrevpellkftcnathelvvrtprsvrrlsrtikgveyfevitfemgqkkapdgriv
elvkevsksypisegperanelvesyrkasnkayfewtieardlsllgshvrkatyqtya
Xcrgfyfelqelkeddyygitlsddsdhqfllanqvvvhn

Sequence, based on observed residues (ATOM records):

>d1vdea1 b.86.1.2 (A:1-180,A:416-454) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae)}
cfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksqhrahk
sdssrevpellkftcnathelvvrtprsvrrlevitfemgqkkapdgrivelvkevsksy
pisegperanelvesyrkasnkayfewtieardlsllgshvrkatyqtyaXcrgfyfelq
elkeddyygitlsddsdhqfllanqvvvhn

Timeline for d1vdea1:

• d1vdea1 first appeared (with stable ids) in SCOP 1.55
  
• d1vdea1 appears in SCOP 1.65
  
• d1vdea1 appears in SCOP 1.69
  
• d1vdea1 appears in the current release, SCOPe 2.08