SCOP 1.69: Domain d1ef0b1: 1ef0 B:1-180,B:416-458

Lineage for d1ef0b1 (1ef0 B:1-180,B:416-458)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.86: Hedgehog/intein (Hint) domain [51293] (1 superfamily)
   complex fold made of five beta-hairpin units and a b-ribbon arc

4. Superfamily b.86.1: Hedgehog/intein (Hint) domain [51294] (2 families)
   duplication: contains two intertwined structural repeats

5. Family b.86.1.2: Intein (protein splicing domain) [51298] (4 proteins)

6. Protein VMA1-derived endonuclease (VDE) PI-Scei intein [51299] (1 species)
   also contains a homing endonuclease and DNA-binding domains

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51300] (8 PDB entries)

8. Domain d1ef0b1: 1ef0 B:1-180,B:416-458 [28377]
   Other proteins in same PDB: d1ef0a2, d1ef0a3, d1ef0b2, d1ef0b3
   miniprecursor; a few extra residues are added at the N-terminus

Details for d1ef0b1

PDB Entry: 1ef0, 2.1 Å

PDB Description: crystal structure of pi-scei miniprecursor

SCOP Domain Sequences for d1ef0b1:

Sequence, based on SEQRES records:

>d1ef0b1 b.86.1.2 (B:1-180,B:416-458) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae)}
afakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksqhrahk
sdssrevpellkftcnathelvvrtprsvrrlsrtikgveyfevitfemgqkkapdgriv
elvkevsksypisegperanelvesyrkasnkayfewtieardlsllgshvrkatyqtya
Xcrgfyfelqelkeddyygitlsddsdhqfllanqvvvhacger

Sequence, based on observed residues (ATOM records):

>d1ef0b1 b.86.1.2 (B:1-180,B:416-458) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae)}
afakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqkslkftcn
athelvvrtprsvrrlsrveyfevitfemgqkkapdgrivelvkevsksypisegperan
elvesyrkasnkayfewtieardlsllgshvrkatyqtyaXcrgfyfelqelkeddyygi
tlsddsdhqfllanqvvvhacger

Timeline for d1ef0b1:

• d1ef0b1 first appeared (with stable ids) in SCOP 1.55
  
• d1ef0b1 appears in SCOP 1.67
  
• d1ef0b1 appears in SCOP 1.71
  
• d1ef0b1 appears in the current release, SCOPe 2.08