SCOPe 2.08: Domain d1ef0a1: 1ef0 A:1-180,A:416-455

Lineage for d1ef0a1 (1ef0 A:1-180,A:416-455)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.86: Hedgehog/intein (Hint) domain [51293] (1 superfamily)
   complex fold made of five beta-hairpin units and a b-ribbon arc

4. Superfamily b.86.1: Hedgehog/intein (Hint) domain [51294] (3 families)
   duplication: contains two intertwined structural repeats

5. Family b.86.1.2: Intein (protein splicing domain) [51298] (5 proteins)

6. Protein VMA1-derived endonuclease (VDE) PI-Scei intein [51299] (1 species)
   also contains a homing endonuclease and DNA-binding domains

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51300] (8 PDB entries)
   Uniprot P17255 284-737

8. Domain d1ef0a1: 1ef0 A:1-180,A:416-455 [28376]
   Other proteins in same PDB: d1ef0a2, d1ef0a3, d1ef0b2, d1ef0b3
   miniprecursor; a few extra residues are added at the N-terminus
   complexed with zn

Details for d1ef0a1

PDB Entry: 1ef0, 2.1 Å

PDB Description: crystal structure of pi-scei miniprecursor

PDB Compounds: (A:) pi-scei endonuclease

SCOPe Domain Sequences for d1ef0a1:

Sequence, based on SEQRES records:

>d1ef0a1 b.86.1.2 (A:1-180,A:416-455) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
afakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksqhrahk
sdssrevpellkftcnathelvvrtprsvrrlsrtikgveyfevitfemgqkkapdgriv
elvkevsksypisegperanelvesyrkasnkayfewtieardlsllgshvrkatyqtya
Xcrgfyfelqelkeddyygitlsddsdhqfllanqvvvhac

Sequence, based on observed residues (ATOM records):

>d1ef0a1 b.86.1.2 (A:1-180,A:416-455) VMA1-derived endonuclease (VDE) PI-Scei intein {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
afakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksqhrahk
sdssrevpellkftcnathelvvrtprsvrvitfemgqkkapdgrivelvkevsksypis
egperanelvesyrkasnkayfewtieardlsllgshvrkatyqtyaXcrgfyfelqelk
eddyygitlsddsdhqfllanqvvvhac

Timeline for d1ef0a1:

• d1ef0a1 first appeared (with stable ids) in SCOP 1.55
  
• d1ef0a1 appears in SCOPe 2.07