SCOPe 2.05: Domain d4x5ia_: 4x5i A:

Lineage for d4x5ia_ (4x5i A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.0: automated matches [191485] (1 protein)
   not a true family

6. Protein automated matches [190777] (19 species)
   not a true protein

7. Species Escherichia coli [TaxId:83333] [267798] (7 PDB entries)

8. Domain d4x5ia_: 4x5i A: [280479]
   automated match to d3jw3a_
   complexed with bme, fol, nap

Details for d4x5ia_

PDB Entry: 4x5i, 1.8 Å

PDB Description: ecdhfr complexed with folate and nadp+ at 660 mpa

PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d4x5ia_:

Sequence; same for both SEQRES and ATOM records:

>d4x5ia_ c.71.1.0 (A:) automated matches {Escherichia coli [TaxId: 83333]}
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

Timeline for d4x5ia_:

• d4x5ia_ is new in SCOPe 2.05-stable
  
• d4x5ia_ appears in SCOPe 2.06
  
• d4x5ia_ appears in the current release, SCOPe 2.08