SCOPe 2.08: Domain d5cxra1: 5cxr A:1-196

Lineage for d5cxra1 (5cxr A:1-196)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

4. Superfamily c.52.1: Restriction endonuclease-like [52980] (37 families)

5. Family c.52.1.34: PA N-terminal domain [254166] (3 proteins)
   Pfam PF00603; relationship to endonucleases discussed in PubMed 19194458

6. Protein PA N-terminal domain [254375] (8 species)

7. Species Influenza A virus [TaxId:1305075] [280128] (1 PDB entry)

8. Domain d5cxra1: 5cxr A:1-196 [280129]
   Other proteins in same PDB: d5cxra2
   automated match to d4ln7a_
   complexed with byz, edo, mn, so4

Details for d5cxra1

PDB Entry: 5cxr, 2 Å

PDB Description: influenza endonuclease complexed with 4-bromopyrazole

PDB Compounds: (A:) endonuclease

SCOPe Domain Sequences for d5cxra1:

Sequence; same for both SEQRES and ATOM records:

>d5cxra1 c.52.1.34 (A:1-196) PA N-terminal domain {Influenza A virus [TaxId: 1305075]}
medfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfhfiderges
iivesgdpnallkhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfiei
gvtrrevhiyylekankiksekthihifsftgeematkadytldeesrariktrlftirq
emasrslwdsfrqser

Timeline for d5cxra1:

• d5cxra1 first appeared in SCOPe 2.05, called d5cxra_
  
• d5cxra1 appears in SCOPe 2.07