Lineage for d4raca_ (4rac A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2128255Fold c.61: PRTase-like [53270] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
  4. 2128256Superfamily c.61.1: PRTase-like [53271] (3 families) (S)
  5. 2128257Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (16 protein domains)
  6. 2128349Protein Hypoxanthine-guanine PRTase (HGPRTase) [53283] (3 species)
  7. 2128350Species Human (Homo sapiens) [TaxId:9606] [53284] (19 PDB entries)
  8. 2128375Domain d4raca_: 4rac A: [280046]
    automated match to d3gepa_
    complexed with 3l4, mg

Details for d4raca_

PDB Entry: 4rac (more details), 2.05 Å

PDB Description: aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, plasmodium falciparum and vivax 6- oxopurine phosphoribosyltransferases and their pro-drugs as antimalarial agents
PDB Compounds: (A:) hypoxanthine-guanine phosphoribosyltransferase

SCOPe Domain Sequences for d4raca_:

Sequence, based on SEQRES records: (download)

>d4raca_ c.61.1.1 (A:) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d4raca_ c.61.1.1 (A:) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4raca_:

Click to download the PDB-style file with coordinates for d4raca_.
(The format of our PDB-style files is described here.)

Timeline for d4raca_: