SCOPe 2.05: Domain d5ew3a_: 5ew3 A:

Lineage for d5ew3a_ (5ew3 A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)

8. Domain d5ew3a_: 5ew3 A: [279928]
   automated match to d4agca_
   complexed with 5t2

Details for d5ew3a_

PDB Entry: 5ew3, 2.5 Å

PDB Description: human vascular endothelial growth factor receptor 2 (kdr) kinase domain in complex with aal993

PDB Compounds: (A:) Vascular endothelial growth factor receptor 2

SCOPe Domain Sequences for d5ew3a_:

Sequence, based on SEQRES records:

>d5ew3a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pydaskwefprdrlklgkplgrgafgqvieadafgidktatcrtvavkmlkegathsehr
almselkilihighhlnvvnllgactkpggplmvivefckfgnlstylrskrnefvpykv
apedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkicdfgla
rdiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvllweifslgaspypgvk
ideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfselvehlgnllqana

Sequence, based on observed residues (ATOM records):

>d5ew3a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pydaskwefprdrlklgkplgrgafgqvieadafgidktatcrtvavkmlkegathsehr
almselkilihighhlnvvnllgactkpggplmvivefckfgnlstylrskrnefvpykv
kdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkicdfglplkwmap
etifdrvytiqsdvwsfgvllweifslgaspypgvkideefcrrlkegtrmrapdyttpe
myqtmldcwhgepsqrptfselvehlgnllqana

Timeline for d5ew3a_:

• d5ew3a_ is new in SCOPe 2.05-stable
  
• d5ew3a_ appears in SCOPe 2.06
  
• d5ew3a_ appears in the current release, SCOPe 2.08