SCOPe 2.05: Domain d5d3za_: 5d3z A:

Lineage for d5d3za_ (5d3z A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.22: Thioesterase domain of polypeptide, polyketide and fatty acid synthases [69584] (4 proteins)
   Pfam PF00975

6. Protein Erythromycin polyketide synthase [69585] (1 species)
   synonym: 6-deoxyerythronolide synthase

7. Species Saccharopolyspora erythraea [TaxId:1836] [69586] (4 PDB entries)

8. Domain d5d3za_: 5d3z A: [279805]
   automated match to d1keza_
   complexed with 1pe, 57h, ca

Details for d5d3za_

PDB Entry: 5d3z, 2.1 Å

PDB Description: crystal structure of the thioesterase domain of deoxyerythronolide b synthase in complex with a small phosphonate inhibitor

PDB Compounds: (A:) Erythronolide synthase, modules 5 and 6

SCOPe Domain Sequences for d5d3za_:

Sequence, based on SEQRES records:

>d5d3za_ c.69.1.22 (A:) Erythromycin polyketide synthase {Saccharopolyspora erythraea [TaxId: 1836]}
ssalrdgyrqagvsgrvrsyldllaglsdfrehfdgsdgfsldlvdmadgpgevtvicca
gtaaisgpheftrlagalrgiapvravpqpgyeegeplpssmaavaavqadavirtqgdk
pfvvaghsagalmayalatelldrghpprgvvlidvyppghqdamnawleeltatlfdre
tvrmddtrltalgaydrltgqwrpretglptllvsagepmgpwpddswkptwpfehdtva
vpgdhftmvqehadaiarhidawlg

Sequence, based on observed residues (ATOM records):

>d5d3za_ c.69.1.22 (A:) Erythromycin polyketide synthase {Saccharopolyspora erythraea [TaxId: 1836]}
ssalrdgyrqagvsgrvrsyldllaglsdfrehfdgsdgfsldlvdmadgpgevtvicca
gtaaisgpheftrlagalrgiapvravpqpgyeegeplpssmaavaavqadavirtqgdk
pfvvaghsagalmayalatelldrghpprgvvlidvyppqdamnawleeltatlfdretv
rmddtrltalgaydrltgqwrpretglptllvsagepmgpwpddswkptwpfehdtvavp
gdhftmvqehadaiarhidawlg

Timeline for d5d3za_:

• d5d3za_ is new in SCOPe 2.05-stable
  
• d5d3za_ appears in SCOPe 2.06
  
• d5d3za_ appears in the current release, SCOPe 2.08