SCOPe 2.08: Domain d4x2qd_: 4x2q D:

Lineage for d4x2qd_ (4x2q D:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.1: ALDH-like [53721] (6 proteins)

6. Protein automated matches [190401] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189906] (28 PDB entries)

8. Domain d4x2qd_: 4x2q D: [279765]
   automated match to d1ag8a_
   complexed with nad

Details for d4x2qd_

PDB Entry: 4x2q, 2.94 Å

PDB Description: crystal structure of human aldehyde dehydrogenase, aldh1a2

PDB Compounds: (D:) Retinal dehydrogenase 2

SCOPe Domain Sequences for d4x2qd_:

Sequence, based on SEQRES records:

>d4x2qd_ c.82.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lpsptpnleikytkifinnewqnsesgrvfpvynpatgeqvcevqeadkadidkavqaar
lafslgsvwrrmdasergrlldkladlverdravlatmeslnggkpflqafyvdlqgvik
tfryyagwadkihgmtipvdgdyftftrhepigvcgqiipwnfpllmfawkiapalccgn
tvvikpaeqtplsalymgalikeagfppgvinilpgygptagaaiashigidkiaftgst
evgkliqeaagrsnlkrvtlelggkspniifadadldyaveqahqgvffnqgqcctagsr
ifveesiyeefvrrsverakrrvvgspfdptteqgpqidkkqynkileliqsgvaegakl
ecggkglgrkgffieptvfsnvtddmriakeeifgpvqeilrfktmdevierannsdfgl
vaavftndinkaltvssamqagtvwincynalnaqspfggfkmsgngremgefglreyse
vktvtvkipqkns

Sequence, based on observed residues (ATOM records):

>d4x2qd_ c.82.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lpsptpnleikytkifinnewqnsesgrvfpvynpatgeqvcevqeadkadidkavqaar
lafslgsvwrrmdasergrlldkladlverdravlatmeslnggkpflqafyvdlqgvik
tfryyagwadkihgmtipvdgdyftftrhepigvcgqiipwnfpllmfawkiapalccgn
tvvikpaeqtplsalymgalikeagfppgvinilpgygptagaaiashigidkiaftgst
evgkliqeaagrsnlkrvtlelggkspniifadadldyaveqahqgvffnqgqcctagsr
ifveesiyeefvrrsverakrrvvgspfdptteqgpqidkkqynkileliqsgvaegakl
ecggkglgrkgffieptvfsnvtddmriakeeifgpvqeilrfktmdevierannsdfgl
vaavftndinkaltvssamqagtvwincynagefglreysevktvtvkipqkns

Timeline for d4x2qd_:

• d4x2qd_ first appeared in SCOPe 2.05
  
• d4x2qd_ appears in SCOPe 2.07