SCOPe 2.08: Domain d4xtaa_: 4xta A:

Lineage for d4xtaa_ (4xta A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (172 PDB entries)
   Uniprot P37231 232-505

8. Domain d4xtaa_: 4xta A: [279378]
   automated match to d3kdub_
   complexed with dif

Details for d4xtaa_

PDB Entry: 4xta, 2.5 Å

PDB Description: mechanisms of ppargamma activation by non-steroidal anti-inflammatory drugs

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d4xtaa_:

Sequence, based on SEQRES records:

>d4xtaa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
sadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkhi
tplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiy
tmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaif
iaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivt
ehvqllqvikktetdmslhpllqeiy

Sequence, based on observed residues (ATOM records):

>d4xtaa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
sadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkevairi
fqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvli
segqgfmtreflkslrkpfgmepkfefavkfnalelddsdlaifiaviilsgdrpgllnv
kpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdl
hpllqeiy

Timeline for d4xtaa_:

• d4xtaa_ first appeared in SCOPe 2.05
  
• d4xtaa_ appears in SCOPe 2.07