SCOPe 2.06: Domain d4xtab_: 4xta B:

Lineage for d4xtab_ (4xta B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (113 PDB entries)
   Uniprot P37231 232-505

8. Domain d4xtab_: 4xta B: [279377]
   automated match to d3kdub_
   complexed with dif

Details for d4xtab_

PDB Entry: 4xta, 2.5 Å

PDB Description: mechanisms of ppargamma activation by non-steroidal anti-inflammatory drugs

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d4xtab_:

Sequence, based on SEQRES records:

>d4xtab_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
sadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkhi
tplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiy
tmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaif
iaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivt
ehvqllqvikktetdmslhpllqeiykd

Sequence, based on observed residues (ATOM records):

>d4xtab_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
sadlralakhlydsyiksfpltkakarailtgktkspfviydmnslmvairifqgcqfrs
veavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmt
reflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiedi
qdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdhpllqei
ykd

Timeline for d4xtab_:

• d4xtab_ first appeared in SCOPe 2.05
  
• d4xtab_ appears in SCOPe 2.07
  
• d4xtab_ appears in the current release, SCOPe 2.08