Lineage for d4rs1a_ (4rs1 A:)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2705447Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 2705448Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 2705548Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)
  6. 2705560Protein Granulocyte-macrophage colony-stimulating factor (GM-CSF) [47289] (1 species)
  7. 2705561Species Human (Homo sapiens) [TaxId:9606] [47290] (10 PDB entries)
  8. 2705567Domain d4rs1a_: 4rs1 A: [279338]
    automated match to d1csga_
    complexed with gol, nag

Details for d4rs1a_

PDB Entry: 4rs1 (more details), 2.68 Å

PDB Description: crystal structure of receptor-cytokine complex
PDB Compounds: (A:) granulocyte-macrophage colony-stimulating factor

SCOPe Domain Sequences for d4rs1a_:

Sequence, based on SEQRES records: (download)

>d4rs1a_ a.26.1.2 (A:) Granulocyte-macrophage colony-stimulating factor (GM-CSF) {Human (Homo sapiens) [TaxId: 9606]}
ehvnaiqearrllnlsrdtaaemnetvevisemfdlqeptclqtrlelykqglrgsltkl
kgpltmmashykqhcpptpetscatqiitfesfkenlkdfllvipfdcwepv

Sequence, based on observed residues (ATOM records): (download)

>d4rs1a_ a.26.1.2 (A:) Granulocyte-macrophage colony-stimulating factor (GM-CSF) {Human (Homo sapiens) [TaxId: 9606]}
ehvnaiqearrllnlsnetvevisemfdlqeptclqtrlelykqglrgsltklkgpltmm
ashykqhcpptpetscatqiitfesfkenlkdfllvipfdcwepv

SCOPe Domain Coordinates for d4rs1a_:

Click to download the PDB-style file with coordinates for d4rs1a_.
(The format of our PDB-style files is described here.)

Timeline for d4rs1a_: