Lineage for d5axqa_ (5axq A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2342123Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2342124Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2342564Family a.211.1.0: automated matches [191566] (1 protein)
    not a true family
  6. 2342565Protein automated matches [190983] (9 species)
    not a true protein
  7. 2342579Species Human (Homo sapiens) [TaxId:9606] [188676] (122 PDB entries)
  8. 2342680Domain d5axqa_: 5axq A: [279117]
    automated match to d4lm1a_
    complexed with 4lk, 4lp, mg, zn

Details for d5axqa_

PDB Entry: 5axq (more details), 1.77 Å

PDB Description: crystal structure of the catalytic domain of pde10a complexed with highly potent and brain-penetrant pde10a inhibitor with 2-oxindole scaffold
PDB Compounds: (A:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d5axqa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5axqa_ a.211.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d5axqa_:

Click to download the PDB-style file with coordinates for d5axqa_.
(The format of our PDB-style files is described here.)

Timeline for d5axqa_: