SCOPe 2.08: Domain d5a86a_: 5a86 A:

Lineage for d5a86a_ (5a86 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (171 PDB entries)

8. Domain d5a86a_: 5a86 A: [278281]
   automated match to d1m13a_
   complexed with d7e

Details for d5a86a_

PDB Entry: 5a86, 2.25 Å

PDB Description: structure of pregnane x receptor in complex with a sphingosine 1- phosphate receptor 1 antagonist

PDB Compounds: (A:) Nuclear receptor subfamily 1 group I member 2

SCOPe Domain Sequences for d5a86a_:

Sequence, based on SEQRES records:

>d5a86a_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lteeqrmmirelmdaqmktfdttfshfknfrlpgvlssgcelpeslqapsreeaakwsqv
rkdlcslkvslqlrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvis
yfrdlpiedqisllkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqlllep
mlkfhymlkklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrp
qpahrflflkimamltelrsinaqhtqrllriqdihpfatplmqelfgit

Sequence, based on observed residues (ATOM records):

>d5a86a_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lteeqrmmirelmdaqmktfdttfshfknfrlpgveeaakwsqvrkdlcslkvslqlrge
dgsvwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpiedqisllkg
aafelcqlrfntvfnaetgtwecgrlsycledtaqqlllepmlkfhymlkklqlheeeyv
lmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflflkimamltelr
sinaqhtqrllriqdihpfatplmqelfgit

Timeline for d5a86a_:

• d5a86a_ first appeared in SCOPe 2.05
  
• d5a86a_ appears in SCOPe 2.07