Lineage for d5cepa_ (5cep A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2984752Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2984753Protein automated matches [190417] (37 species)
    not a true protein
  7. 2984910Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)
  8. 2985824Domain d5cepa_: 5cep A: [278051]
    automated match to d2j7ta_
    complexed with 50e

Details for d5cepa_

PDB Entry: 5cep (more details), 1.99 Å

PDB Description: dlk in complex with inhibitor n-(1-isopropyl-5-(piperidin-4-yl)-1h- pyrazol-3-yl)-4-(trifluoromethyl)pyridin-2-amine
PDB Compounds: (A:) Mitogen-activated protein kinase kinase kinase 12

SCOPe Domain Sequences for d5cepa_:

Sequence, based on SEQRES records: (download)

>d5cepa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lwevpfeeildlqwvgsgaqgavflgrfhgeevavkkvrdlketdikhlrklkhpniitf
kgvctqapcycilmefcaqgqlyevlragrpvtpsllvdwsmgiaggmnylhlhkiihrd
lkspnmlityddvvkisdfgtskelsdkstkmsfagtvawmapevirnepvsekvdiwsf
gvvlwelltgeipykdvdssaiiwgvgsnslhlpvpsscpdgfkillrqcwnskprnrps
frqillhldiasadvlstpqetyfksqaewreevklhfekik

Sequence, based on observed residues (ATOM records): (download)

>d5cepa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lwevpfeeildlqwvgsgaqgavflgrfhgeevavkkvrdlketdikhlrklkhpniitf
kgvctqapcycilmefcaqgqlyevlragrpvtpsllvdwsmgiaggmnylhlhkiihrd
lkspnmlityddvvkisdfgfagtvawmapevirnepvsekvdiwsfgvvlwelltgeip
ykdvdssaiiwgvgsnslhlpvpsscpdgfkillrqcwnskprnrpsfrqillhldiasa
dvlstpqetyfksqaewreevklhfekik

SCOPe Domain Coordinates for d5cepa_:

Click to download the PDB-style file with coordinates for d5cepa_.
(The format of our PDB-style files is described here.)

Timeline for d5cepa_: