Lineage for d5c7xa1 (5c7x A:9-110)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2315782Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 2315783Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 2315881Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)
  6. 2315893Protein Granulocyte-macrophage colony-stimulating factor (GM-CSF) [47289] (1 species)
  7. 2315894Species Human (Homo sapiens) [TaxId:9606] [47290] (8 PDB entries)
  8. 2315904Domain d5c7xa1: 5c7x A:9-110 [278026]
    Other proteins in same PDB: d5c7xa2, d5c7xb2, d5c7xl1, d5c7xl2, d5c7xn1, d5c7xn2
    automated match to d2gmfa_
    complexed with peg, pg6, pge

Details for d5c7xa1

PDB Entry: 5c7x (more details), 2.95 Å

PDB Description: crystal structure of mor04357, a neutralizing anti-human gm-csf antibody fab fragment in complex with human gm-csf
PDB Compounds: (A:) granulocyte-macrophage colony-stimulating factor

SCOPe Domain Sequences for d5c7xa1:

Sequence, based on SEQRES records: (download)

>d5c7xa1 a.26.1.2 (A:9-110) Granulocyte-macrophage colony-stimulating factor (GM-CSF) {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d5c7xa1 a.26.1.2 (A:9-110) Granulocyte-macrophage colony-stimulating factor (GM-CSF) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d5c7xa1:

Click to download the PDB-style file with coordinates for d5c7xa1.
(The format of our PDB-style files is described here.)

Timeline for d5c7xa1: